Lowville 23 and Scordo scored on a 3-yard run four plays later to make it 6-0.
After Lowville went three and out, General Brown put together its only semblance of a drive. Taking over at its own 41, the Lions were in the end zone in eight plays with Allen going the final five yards for the score. Quarterback Nick Frears tacked on the 2-point conversion.
Lowville fumbled the ensuing kickoff, General Brown recovered, and Klusacek went 16 yards untouched for the third Lions' score.
Another Lowville miscue, this time a snap over the punter's head, led to a short TD by Allen. And on Lowville's next possession, Klusacek stepped in front of a Jeremy Kingsley pass and raced down the sidelines for a 51-yard score in the final seconds of the opening quarter.
Klusacek also broke free for a 64-yard scoring run in the second quarter.
"Our offensive line did a great job,'' Klusacek said. "And a lot of our sophomores really did a nice job for us tonight.''
Frears has the luxury of playing three versatile runners, or what he calls his three-headed monster of Klusacek, Scordo and Allen. "It allows us to keep them all fresh and give them all some touches.''
Said Scordo: "We've got some really good skill players, so I figured we could move the ball. But we've worked really hard on our conditioning and hopefully that will help us when we get in really tough games.''
While the Lions couldn't find much to complain about, first-year Lowville coach Josh Coffman's club didn't do much right.
"It's frustrating to start like that,'' said Coffman, who took over from Rob Goss, who is assisting him this season. "We were kind of in quick sand early. We got in a hole and couldn't get out.''
Lowville didn't manage a first down until early in the second quarter and finished with just 156 total yards.
Junior quarter Jeremy Kingsley had an awful game, going 4-for-19 for just 57 yards and those two big interceptions.
"Their studs played well and ours didn't,'' Coffman said. "Hopefully, we'll find something good and put things together the rest of the season."